Sam Griffith

Samantha Griffith is an an Attending Physician and the Head of Cardiothoracic Surgery at Lakeshore Sentinel Hospital.

Early life
Samantha Griffith was born to Rob Griffith and Vivian Katz, who would later divorce. At some point in her life, Sam was riding as a passenger in her father's car until they were involved in an accident after Rob had sped. Due to the accident, Sam received heart surgery, leaving her with a scar on her chest and causing her father's personality to change and for him to become more distant.

Sam later became involved in a relationship with Caleb Tucker.

"Pilot"
In 2021, after Sam had chased and stopped a nervous patient named David Ferguson, she explained to him that his heart surgeon, Rob, was in her opinion, the best cardiothoracic surgeon. As Sam described Rob and his attention to detail, she watched as he had arrived outside the hospital and cleaned a smudge off of the back of his car. Around this time, Sam had considered a career change and would have discussions about it, including with her boyfriend Caleb. During Ferguson's surgery, Rob changed the planned prodecude, leading to a disagreement with Sam.

After the surgery, Sam and Rob continued to argue about his methods until they were alerted about a ten-car pileup on I-94. Sam and Rob hurried to the lobby to treat a woman who was coding. They walked past and man a woman, with the man asking Rob to treat his wife, who had a gash on her forehead. Rob quickly looked at her injury and told the man that she was fine. The husband angrily confronted Rob, drawing his attention away from another man standing suspiciously in the lobby. When Rob turned to face the husband, he was shot through the back. Rob fell to the ground, clutching his chest and the shooter was dragged to the floor. Rob then fell into a coma.

Six months later, in 2022, Sam had broken up with Caleb and had remained employed at the hospital. She prepared a speech about taking over Rob's position and soon met Malcolm A. Kingsley, the son of one of the hospital's donors. Soon after, Vivian alerted Sam that Rob had woken up from his coma.

Behind the Scenes
Sam Griffith was portrayed by Sophia Bush in Season 1 of Good Sam.